Total Hyphema with Light Perception Vision Managed by Anterior Chamber Washout: A Case Report
Keywords:
Hyphema, ocular trauma, anterior chamber washout, secondary glaucoma, cataract surgeryAbstract
IntroductionOcular trauma represents a major etiology of monocular blindness and visual morbidity, frequently requiring emergent ophthalmological evaluation to prevent permanent deficits.1 Traumatic hyphema, defined as the presence of blood within the anterior chamber, typically arises from blunt or penetrating force that disrupts the vascular integrity of the iris or ciliary body.3 While most hyphemas are self-limiting, high-grade presentations (Grade III and IV) pose a significant risk for secondary complications such as ocular hypertension, secondary glaucoma, and corneal blood staining.5 The management of these cases is particularly complex in the immediate postoperative period following intraocular surgery, where the structural stability of the eye is already compromised.8
Case IllustrationA 64-year-old male presented with a chief complaint of sudden vision loss, severe ocular pain, and redness in the right eye (OD) after an accidental hand strike during sleep. The patient was one week postoperative following a Small Incision Cataract Surgery (SICS). Initial examination revealed a visual acuity of light perception (LP), an intraocular pressure (IOP) of 21.9 mmHg, and a Grade IV total hyphema with evidence of fibrin clots. Slit-lamp biomicroscopy confirmed corneal edema and a hazy anterior chamber. Despite three days of intensive conservative management using postural therapy, topical steroids, anti-glaucoma agents, and systemic antifibrinolytics, the visual acuity did not improve. Consequently, a surgical anterior chamber washout was performed.
DiscussionTotal hyphema, often referred to as an "eight-ball" hyphema when clotted and deoxygenated, necessitates a careful balance between medical observation and surgical intervention.3 In this case, the recent surgical history and the stagnant nature of the clotted blood increased the risk of permanent endothelial damage and optic neuropathy.6 The choice of an anterior chamber washout as a minimally invasive procedure was pivotal in evacuating the blood and restoring aqueous dynamics.8 Pharmacological support using Indonesian-branded medications such as Bralifex Plus and Hyaloph, combined with comprehensive antioxidant supplements like Asta Plus and Retivit Plus, facilitated the recovery of the ocular surface and neuroprotection.13
ConclusionAnterior chamber washout is an effective and safe intervention for non-resolving total hyphema in the early postoperative phase.8 Prompt surgical evacuation, when medical therapy fails to produce clinical improvement within 72 hours, is essential to prevent irreversible complications and ensure significant visual recovery.6
References
Seeing Eye to Eye with Traumatic Hyphema: Case Report and Management Guidelines - Scirp.org., diakses April 7, 2026, https://www.scirp.org/pdf/crcm_2772284.pdf
Management of Traumatic Hyphema and Prevention of Its Complications - PMC, diakses April 7, 2026, https://pmc.ncbi.nlm.nih.gov/articles/PMC8291460/
Hyphema: Diagnosis and Management - EyeRounds.org, diakses April 7, 2026, https://eyerounds.org/cases/345-hyphema.htm
Hyphema - StatPearls - NCBI Bookshelf - NIH, diakses April 7, 2026, https://www.ncbi.nlm.nih.gov/books/NBK507802/
Traumatic Glaucoma - StatPearls - NCBI Bookshelf, diakses April 7, 2026, https://www.ncbi.nlm.nih.gov/books/NBK585060/
Corneal Blood Staining after Complicated Cataract Surgery - PMC, diakses April 7, 2026, https://pmc.ncbi.nlm.nih.gov/articles/PMC6180266/
Understanding Traumatic Hyphema Blood in the Anterior Chamber - Hatboro, diakses April 7, 2026, https://hatboro.refocuseyedoctors.com/article/understanding-traumatic-hyphema-blood-in-the-anterior-chamber/
Case Report: Multiple anterior chamber paracentesis or washout for a large hyphema following vitrectomy with silicone oil tamponade - Frontiers, diakses April 7, 2026, https://www.frontiersin.org/journals/ophthalmology/articles/10.3389/fopht.2025.1621845/full
Traumatic aniridia in a pseudophakic patient 6 years following surgery - PMC, diakses April 7, 2026, https://pmc.ncbi.nlm.nih.gov/articles/PMC3280105/
Hyphema due to blunt injury: a review of 118 patients - PMC, diakses April 7, 2026, https://pmc.ncbi.nlm.nih.gov/articles/PMC3340623/
Hyphema – from the effect to the cause, diakses April 7, 2026, https://revistamedicinamilitara.ro/wp-content/uploads/2018/05/Hyphema-%E2%80%93-from-the-effect-to-the-cause.pdf
Use of an anterior chamber maintainer in the surgical management of traumatic hyphaemas - OphEd, diakses April 7, 2026, https://www.ophed.com/system/files/2012/09/useofacminthesurgical-3490-3490.pdf
Profilaksis antibiotik untuk abrasi kornea, diakses April 7, 2026, https://pmc.ncbi.nlm.nih.gov/articles/PMC9139695/
Clinical Applications of Astaxanthin in the Treatment of Ocular Diseases: Emerging Insights - PMC, diakses April 7, 2026, https://pmc.ncbi.nlm.nih.gov/articles/PMC7281326/
Retivit - Kegunaan, Efek Samping, Dosis dan Aturan Pakai - Halodoc, diakses April 7, 2026, https://www.halodoc.com/obat-dan-vitamin/retivit-plus-10-kaplet
Traumatic Glaucoma in Children, diakses April 7, 2026, https://www.jocgp.com/doi/10.5005/jp-journals-10008-1162
Traumatic Hyphaema: A Case Report - Scientific Publications, diakses April 7, 2026, https://www.scipublications.com/journal/index.php/gjmcr/article/view/483
Contemporary aspects in the prognosis of traumatic hyphemas - PMC - NIH, diakses April 7, 2026, https://pmc.ncbi.nlm.nih.gov/articles/PMC2709009/
Secondary Glaucoma: Glaucoma Associated with Acquired Conditions, diakses April 7, 2026, https://www.aao.org/education/disease-review/secondary-glaucoma-glaucoma-associated-with-acquir
Characteristics of Traumatic Cataract Wound Dehiscence | Ento Key, diakses April 7, 2026, https://entokey.com/characteristics-of-traumatic-cataract-wound-dehiscence/
Traumatic hyphema - American Nurse Journal, diakses April 7, 2026, https://www.myamericannurse.com/traumatic-hyphema/
Hyphema (Bleeding in Eye): Diagnosis, Symptoms & Causes - Cleveland Clinic, diakses April 7, 2026, https://my.clevelandclinic.org/health/diseases/22586-hyphema
Recent Advances and the Mechanism of Astaxanthin in Ophthalmological Diseases - PMC, diakses April 7, 2026, https://pmc.ncbi.nlm.nih.gov/articles/PMC9142330/
Case Report: Multiple anterior chamber paracentesis or washout for a large hyphema following vitrectomy with silicone oil tamponade - PMC, diakses April 7, 2026, https://pmc.ncbi.nlm.nih.gov/articles/PMC12708267/
How Astaxanthin Can Help Protect Your Eyes - Sea Salts of Hawaii, diakses April 7, 2026, https://www.seasaltsofhawaii.com/blogs/recipes/how-astaxanthin-can-help-protect-your-eyes
Sodium hyaluronate eye drops treatment for superficial corneal abrasion caused by mechanical damage: a randomized clinical trial in the People's Republic of China, diakses April 7, 2026, https://www.dovepress.com/sodium-hyaluronate-eye-drops-treatment-for-superficial-corneal-abrasio-peer-reviewed-fulltext-article-DDDT
Visual acuity recovery following traumatic hyphema in a pediatric population - PMC, diakses April 7, 2026, https://pmc.ncbi.nlm.nih.gov/articles/PMC5916317/
A Case Report: Complicated Traumatic Hyphaema - Australian Orthoptic Journal, diakses April 7, 2026, https://www.aojournal.com.au/static/uploads/files/aoj20134504-wflfofjctawa.pdf
Seeing Eye to Eye with Traumatic Hyphema: Case Report and Management Guidelines, diakses April 7, 2026, https://www.scirp.org/journal/paperinformation?paperid=150006
Global Current Practice Patterns for the Management of Hyphema - PMC, diakses April 7, 2026, https://pmc.ncbi.nlm.nih.gov/articles/PMC9524379/
Incidence of and Risk Factors for Postoperative Hyphema After 23-Gauge Pars Plana Vitrectomy for Proliferative Diabetic Retinopathy - Dove Medical Press, diakses April 7, 2026, https://www.dovepress.com/incidence-of-and-risk-factors-for-postoperative-hyphema-after-23-gauge-peer-reviewed-fulltext-article-IJGM
SODIUM HYALURONATE Ophthalmic Solution 0.1%"TS" | Kusuri-no-Shiori(Drug Information Sheet), diakses April 7, 2026, https://www.rad-ar.or.jp/siori/english/search/result?n=33416
Medical interventions for traumatic hyphema - PMC - NIH, diakses April 7, 2026, https://pmc.ncbi.nlm.nih.gov/articles/PMC10010597/
ASTA PLUS - PT. Simex Pharmaceutical Indonesia, diakses April 7, 2026, https://www.simex.co.id/detail_product.php?nama_product=ASTAPLUS
ASTA PLUS 6 KAPLET - Kegunaan, Efek Samping, Dosis dan Aturan Pakai - Halodoc, diakses April 7, 2026, https://www.halodoc.com/obat-dan-vitamin/asta-plus-6-kaplet
Retivit Plus Tablet - Manfaat, Dosis, Efek Samping -... - K24Klik, diakses April 7, 2026, https://www.k24klik.com/p/RETIVIT-PLUS-TAB-870
Anterior Chamber Washout - American Academy of Ophthalmology, diakses April 7, 2026, https://www.aao.org/education/annual-meeting-video/anterior-chamber-washout
Bilateral Angle Recession and Chronic Post-Traumatic Glaucoma: A Review of the Literature and a Case Report - PMC, diakses April 7, 2026, https://pmc.ncbi.nlm.nih.gov/articles/PMC10532958/
Traumatic hyphema - WikEM, diakses April 7, 2026, https://wikem.org/wiki/Traumatic_hyphema
Corneal Blood Staining - MillennialEYE, diakses April 7, 2026, https://millennialeye.com/articles/2017-mar-apr/corneal-blood-staining/
How long before the blood clears from my eye after getting a hyphema?, diakses April 7, 2026, https://www.aao.org/eye-health/ask-ophthalmologist-q/how-long-before-blood-clears-from-my-eye-after-get
Tobramycin/Dexamethasone (TobraDex): Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD, diakses April 7, 2026, https://www.webmd.com/drugs/tobramycin-dexamethasone-tobradex
Bralifex Plus | PDF - Scribd, diakses April 7, 2026, https://id.scribd.com/doc/280224447/Bralifex-Plus
Traumatic Hyphaema: A Case Report - ResearchGate, diakses April 7, 2026, https://www.researchgate.net/publication/365406026_Traumatic_Hyphaema_A_Case_Report
Medical interventions for traumatic hyphema - Johns Hopkins University, diakses April 7, 2026, https://pure.johnshopkins.edu/en/publications/medical-interventions-for-traumatic-hyphema-10/
CN102697713B - Sodium hyaluronate eye drops and a preparation method thereof - Google Patents, diakses April 7, 2026, https://patents.google.com/patent/CN102697713B/en
Sodium Hyaluronate 0.2% Eye Drops - University Hospitals Sussex NHS Foundation Trust, diakses April 7, 2026, https://www.uhsussex.nhs.uk/resources/sodium-hyaluronate-0-2-eye-drops/
Sodium hyaluronate eye drops treatment for superficial corneal abrasion caused by mechanical damage: a randomized clinical trial in the People's Republic of China - PMC, diakses April 7, 2026, https://pmc.ncbi.nlm.nih.gov/articles/PMC4322606/
Retivit Plus Tablet - Manfaat, Dosis, Efek Samping -... - K24Klik, diakses April 7, 2026, https://www.k24klik.com/p/-870
eye health+ | supplement with astaxanthin, lutein, and zeaxanthin - the mindbodygreen shop, diakses April 7, 2026, https://shop.mindbodygreen.com/products/eye-health
Effects of Astaxanthin, Lutein, and Zeaxanthin on Eye–Hand Coordination and Smooth-Pursuit Eye Movement after Visual Display Terminal Operation in Healthy Subjects: A Randomized, Double-Blind Placebo-Controlled Intergroup Trial - PMC, diakses April 7, 2026, https://pmc.ncbi.nlm.nih.gov/articles/PMC10054128/
Comparison of the protective effects of astaxanthin, lutein, and zeaxanthin from AMD-related vision loss in zebrafish | IOVS, diakses April 7, 2026, https://iovs.arvojournals.org/article.aspx?articleid=2796505
Comparative Efficiency of Lutein and Astaxanthin in the Protection of Human Corneal Epithelial Cells In Vitro from Blue-Violet Light Photo-Oxidative Damage - MDPI, diakses April 7, 2026, https://www.mdpi.com/2076-3417/12/3/1268
Visual acuity recovery following traumatic hyphema in a pediatric population., diakses April 7, 2026, https://www.ophth.wisc.edu/blog/2018/04/01/visual-acuity-recovery-following-traumatic-hyphema-in-a-pediatric-population/
(PDF) Poor final visual outcome after traumatic hyphema: A retrospective study of associated factors - ResearchGate, diakses April 7, 2026, https://www.researchgate.net/publication/276195639_Poor_final_visual_outcome_after_traumatic_hyphema_A_retrospective_study_of_associated_factors
Downloads
Published
Issue
Section
License
Copyright (c) 2026 Rofwiun, Nurul Elyana (Author)

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
Authors publishing here keep copyright but grant the journal first publication rights, under a Creative Commons Attribution-NonCommercial 4.0 License. They can distribute their work non-exclusively elsewhere with an acknowledgment of its first publication in this journal. Posting the work online before and during submission for earlier and greater citation is encouraged, reflecting Open Access benefits.
