Complication and Management of Diabetic Retinopathy

Complication and Management of Diabetic Retinopathy

Authors

  • Vivi Cahyani Student, Medical Doctor Education Program, Faculty of Medicine, Universitas Muslim Indonesia.
  • Suliati P. Amir Department of Ophthalmology, Faculty of Medicine, Universitas Muslim Indonesia.
  • Hanna Aulia Namirah Department of Ophthalmology, Faculty of Medicine, Universitas Muslim Indonesia.

Keywords:

Diabetic Retinopathy, Management, Complications, PDR

Abstract

Background: Diabetic retinopathy (DR) is a common microvascular complication of diabetes mellitus that remains a leading cause of preventable blindness worldwide. Chronic hyperglycemia leads to retinal microangiopathy, resulting in progressive damage that may culminate in serious complications. As DR advances, especially into the proliferative stage (PDR), patients may experience vitreous hemorrhage (VH), diabetic macular edema (DME), or tractional retinal detachment (TRD).

Methods: This study is a literature review of ten scientific articles published between 2015 and 2024, focusing on the complications and management of DR.

Results: The literature highlights that the primary treatment modalities for DR include panretinal photocoagulation (PRP), intravitreal anti-VEGF injections, and vitrectomy. PRP is commonly used for high-risk PDR, anti-VEGF for DME or active neovascularization, and vitrectomy for advanced cases with VH or TRD. Management decisions are highly dependent on the stage of DR and the presence of complications.

Conclusion: The management of DR should be adapted to the severity and type of complication. Early diagnosis and timely intervention are crucial to prevent vision loss.

References

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American Academy of Ophthalmology. (2021). Diabetic Retinopathy Preferred Practice Pattern®.

American Diabetes Association. (2014). Diagnosis and Classification of Diabetes Mellitus. Diabetes Care, 37(Supplement_1), S81–S90. https://doi.org/10.2337/dc14-S081

Bahr, T. A., & Bakri, S. J. (2023). Update on the Management of Diabetic Retinopathy: Anti-VEGF Agents for the Prevention of Complications and Progression of Nonproliferative and Proliferative Retinopathy. Life, 13(5), 1098. https://doi.org/10.3390/life13051098

Beaser, R. S., Turell, W. A., & Howson, A. (2018). Strategies to Improve Prevention and Management in Diabetic Retinopathy: Qualitative Insights from a Mixed-Methods Study. Diabetes Spectrum, 31(1), 65–74. https://doi.org/10.2337/ds16-0043

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Singh, R., Farooq, S. A., Mannan, A., Singh, T. G., Najda, A., Grażyna, Z., Albadrani, G. M., Sayed, A. A., & Abdel-Daim, M. M. (2022). Animal models of diabetic microvascular complications: Relevance to clinical features. Biomedicine & Pharmacotherapy, 145, 112305. https://doi.org/10.1016/j.biopha.2021.112305

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Published

2025-08-22

How to Cite

Vivi Cahyani, Suliati P. Amir, and Hanna Aulia Namirah. 2025. “Complication and Management of Diabetic Retinopathy”. The International Journal of Medical Science and Health Research 15 (6): 1-20. https://doi.org/10.70070/knn9mr40.